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Ketamine / Spravato

Adult Psychiatry located in Fort Collins, CO
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Ketamine / Spravato services offered in Fort Collins, CO


Spravato is a new treatment tool that offers relief for about 70% of people who don’t respond to antidepressants. Foremost psychiatrist Josiah Ziegler, DO, has seen the remarkable effects of Spravato in many of his patients at Psychiatric Services of the Rockies. As a trailblazer in the psychiatric field, Dr. Ziegler offers Spravato treatment options through telemedicine and office-based appointments in Fort Collins, Colorado. Call the office or use the provided booking feature to schedule your consultation and evaluation now.

Ketamine / Spravato Q&A

What is Spravato?

Spravato is a drug that gained FDA approval more than 50 years ago. Originally, it was used only during surgery as a safe and reliable anesthetic because it doesn’t depress breathing as many other anesthetics do. 

More recently, Spravato has garnered attention for having rapid effects within the brain of people who have depression and other mental illnesses. In many cases, it provides near-instant relief.

How does Spravato affect the brain?

Spravato works on the neurotransmitters, the brain chemicals that influence your mood. That might sound familiar if you’ve ever taken antidepressants, and it’s true that those drugs also work on neurotransmitters. 

But while antidepressants usually impact serotonin levels, low doses of Spravato ultimately cause a flood of glutamate, which is often called the “master” neurotransmitter. This has a rapid antidepressant effect. 

Spravato works in other ways, too, which researchers don’t fully understand. Currently thinking is that it causes the release of additional chemicals that work like neural fertilizers.

Basically, those chemicals cause new brain neuron connections to spring up. This allows for the development of new healthy thought pathways that can replace the old (harmful) ones.

These unique effects help explain Spravato’s effectiveness when people taking oral antidepressants showed no improvement.

Spravato therapy has led to impressive results in people with depression, anxious depression (depression plus severe anxiety), obsessive-compulsive disorder (OCD), bipolar disorder, and post-traumatic stress disorder (PTSD).

What is the Spravato treatment process?

The Nasal spray (Spravato®) is offered at Psychiatric Services of the Rockies. Spravato is FDA-approved as a treatment for depression that doesn’t improve with the use of two or more antidepressants, known as treatment-resistant depression (TRD). 

To help you get the most out of these sessions, it’s important to understand how we approach this therapy and how you can play an active role in optimizing your outcomes.

1. Setting the right environment

Your comfort and safety are our top priorities. Spravato treatments work best in a calm and soothing environment. During your session, you’ll be in a quiet room with dim lighting and soft, relaxing music. These elements are designed to help you feel at ease and allow you to focus inward without distractions. Think of this as a space where you can let go and trust the process.

2. Preparing for your session

Preparation is key to having a positive experience. Before each session:

- Know what to expect: Spravato can sometimes create a dreamlike or dissociative state. This is normal and often part of the therapeutic process.

- Set an intention: It can be helpful to reflect on what you hope to achieve. Whether it’s gaining clarity, processing emotions, or reducing symptoms, having a goal can guide your experience.

We’ll also be here to answer any questions you have and address any concerns.

3. During the session:

When it’s time for your session, our team will be nearby to support you. Depending on your preferences, we can offer guided techniques such as breathing exercises or gentle prompts to help you stay grounded. The dose of Spravato is tailored specifically to your needs, so you can feel reassured that this treatment is uniquely designed for you.

 

Combining treatments for enhanced benefits:

 

While Spravato is a powerful tool on its own, some patients may see even greater benefits by combining it with other treatments, such as transcranial magnetic stimulation. TMS works by stimulating specific areas of the brain associated with mood regulation and can complement the effects of Spravato. Together, these treatments may enhance your progress and provide a more comprehensive approach to your mental health care.

To find out if Spravato can work for you, call Psychiatric Services of the Rockies or click the online booking feature now.

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